Endocrine Disruptors — The revision of the CLP Regulation

Endocrine disruptors: What to know?

The endocrine system regulates the body’s development through hormones.

Chemicals can be either neutral or may interfere with hormonal system giving adverse effects. As the effects are often belated, it is not evident if a compound has endocrine disrupting properties.

The concern regarding endocrine disruptors is growing.

After a first intervention regarding the cosmetic ingredients that may have potential endocrine-disrupting properties, on December 19, 2022, the European Commission proposed to amend the Regulation on classification, labelling and packaging of chemicals (CLP Regulation (EC) No 1272/2008).

The European Commission proposal

The proposal aims to introduce new hazard classes based on scientific criteria for endocrine disruptors as well as other chemicals which can accumulate in living organisms or enter the water cycle.

The harmonised classification aspires to provide consumers, workers, and businesses easy access to information about those chemicals.

Moreover, the revision wants to improve the communication of chemical hazards to users. Therefore, the European Commission has set mandatory formatting rules (font, size, and colour) to ensure the clarity of the information on the labels.

The label must include essential information; whereas any non-essential additional information can be displayed on a digital label.

The proposal also aims to address the legal gaps in the CLP Regulation regarding online sales. Therefore, the supplier will have to ensure that substances and mixtures sold online comply with the classification, labelling and packaging requirements.

Furthermore, the European Commission will clarify the provisions concerning chemical notifications to poison centres. Relevant actors will have to notify the poison centres in the EU with all the information regarding the chemical, where necessary.

However, as this is a European Commission proposal, the European Parliament and Council will have to approve it following the ordinary legislative procedure. Do not miss our articles — We will keep you updated on the next steps.

Do you wish always to be updated regarding European legislation? Obelis can help you; contact us!

Claudia Argenti

RA Department



European Chemicals Agency. (2022). Endocrine disruptors. Retrieved on 09/01/2023.

European Commission. (19/12/2022). Commission sets up rules to identify endocrine disruptors and long-lasting chemicals and to improve labelling. Retrieved on 09/01/2023.

European Commission. (2022). Endocrine disruptors. Retrieved on 09/01/2023.

European Commission. (19/12/2022). Proposal for a REGULATION OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL amending Regulation (EC) No 1272/2008 of the European Parliament and of the Council on classification, labelling and packaging of substances and mixtures. Retrieved on 09/01/2023.

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