The Scientific Committee [1] has published its final Opinions regarding the safety of the UV-Filter Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate [SCCS/1605/19] and the hair dye ingredient Tetrabromophenol Blue [SCCS/1610/19] on 13 December 2019, after consideration of public comments received during the commenting period.
Tetrabromophenol Blue (C183)
-SUBMISSION IV
In the preliminary Opinion, the substance was considered safe when used in oxidative and non-oxidative hair colouring products with a final on-head concentration of up to 0.2%. Nonetheless, toxicological concerns remained unclear in response to the large composition discrepancies noted between representative market quality batch and that used in the toxicological testing.
The SCCS confirmed its previous findings in its final Opinion : ”Based on the overall weight of evidence derived from the data provided, the SCCS considers Tetrabromophenol Blue (C183) safe when used as a hair dye in oxidative and non-oxidative hair colouring products at a final on-head concentration of up to 0.2%.”
Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate (S87)
-SUBMISSION II
In the first Opinion from 2017, the SCCS requested additional data to exclude concerns regarding genotoxicity and potential skin and eye irritation.
Based on the data submitted, the SCCS concluded that the use of Methoxypropylamino Cyclohexenylidene Ethoxyethylcyanoacetate (S87) is safe as a UV-filter in cosmetic products up to a maximum concentration of 3%.
It should be however noted that this Opinion is not applicable to sprayable products since no data was provided on the related inhalation toxicity. Moreover, it states that in light of the chemical nature of the ingredient, it should not be used in combination with nitro-sating substances, with a consequent nitrosamine overall content to remain below 50 ppb.
03/01/2020
Filippo Chierchini
Regulatory Affairs and Quality Assurance
For more information about clinical evaluation contact our experts today!
[1] European Commission’s Scientific Committee on Consumer Safety